Immortal - The All in One `Longevity Product with world's first Liposomal GHK-Cu -

THE PROBLEM WITH EVERY OTHER LONGEVITY
SUPPLEMENT
The compounds that science has identified as the most powerful drivers of human longevity
have one thing in common: they don't absorb. NMN at 25% bioavailability. Resveratrol at
1%. L-Carnitine at 1%. NAD+ essentially zero without delivery technology. The research is
real. The standard delivery is not.
Immortal solves the delivery problem that makes every other longevity formula a premium-
priced disappointment. Every active compound is encapsulated in a phospholipid bilayer
vesicle — a liposome — that bypasses digestive degradation, fuses directly with cell
membranes, and delivers actives into systemic circulation intact. This is pharmaceutical-
grade delivery science applied to the most researched longevity compounds on earth.

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THE STACK — EVERY INGREDIENT. EVERY
REASON.

Riboflavin (Vitamin B2) — 1mg
Riboflavin is the master regulator of mitochondrial Complex I and Complex II in the electron
transport chain — the very first step in ATP synthesis. Without adequate B2, the entire
energy cascade stalls upstream of everything else in this formula. It also regenerates
glutathione, your primary intracellular antioxidant, keeping oxidative damage in check as
NAD+ metabolism accelerates.
Vitamin B6 — 5mg
B6 is involved in over 100 enzymatic reactions with a specific and critical role in NAD+
biosynthesis via the de novo tryptophan pathway. It is also essential for neurotransmitter
synthesis — serotonin, dopamine, GABA — meaning its absence is felt cognitively long before
any bloodwork flags a deficiency. Included here as a cofactor to support the full NAD+
production cascade that the rest of this formula depends on.
Vitamin B12 — 250mcg
B12 is required for DNA synthesis, myelin sheath maintenance, and the methylation cycle
that keeps homocysteine levels in check. It works synergistically with TMG — also in this
formula — to ensure the methylation demands created by elevated NAD+ metabolism are
fully supported. Elevated homocysteine is one of the most reliable independent predictors of
cardiovascular and neurodegenerative decline. B12 keeps it controlled.
NMN — Nicotinamide Mononucleotide — 250mg | Liposomal 84% vs 25%
standard
NAD+ is the fuel your mitochondria run on. After 40, your levels drop by up to 50%. NMN is
one enzymatic step from NAD+ — the most direct precursor in the human biosynthesis
pathway. A dedicated intestinal transporter called Slc12a8 facilitates direct NMN absorption
and becomes increasingly active with age, suggesting the body itself identifies NMN

replenishment as a longevity priority. More NAD+ means more ATP, activated sirtuins, and
active DNA repair.
NR — Nicotinamide Riboside — 250mg | Liposomal 85% vs 30% standard
Where NMN dominates metabolic and gut tissue, NR's smaller molecular size gives it
superior uptake in neurological tissue via nucleoside transporters most active in the brain
and nervous system. Backed by over 40 completed clinical trials and FDA GRAS status, NR is
the most extensively researched NAD+ precursor in existence. NMN and NR together cover
every tissue type. Either alone leaves gaps. Immortal runs both.
NAD+ — 250mg | Liposomal 65% vs 5% standard
NAD+ cannot cross cell membranes unassisted — making direct supplementation in
standard form essentially futile. Liposomal encapsulation bypasses that barrier completely.
Inside the cell it immediately fuels the electron transport chain, drives ATP synthesis, and
activates the sirtuin family of longevity enzymes. NMN and NR build NAD+ endogenously.
Immortal also delivers it directly. Both pathways firing simultaneously.
Quercetin
Quercetin is a flavonoid senolytic — targeting and clearing senescent "zombie" cells that
accumulate with age and release inflammatory signals that accelerate degeneration in
surrounding healthy tissue. It acts as a shield against free radicals, combats chronic low-
grade inflammation linked to age-related disease, and supports cardiovascular and immune
function. Most effective when paired with fisetin — both are in this formula.
Trans-Resveratrol | Liposomal 90% vs 1% standard
Resveratrol activates SIRT1 — the master longevity sirtuin — which drives PGC-1α, the
primary regulator of mitochondrial biogenesis. More mitochondria. Better mitochondria.
Greater ATP output per cell. Sirtuins require NAD+ as a cofactor, meaning the
NMN/NR/NAD+ stack and resveratrol amplify each other directly and measurably. At 1%
standard bioavailability, resveratrol is one of the most wasted ingredients in the supplement
industry. At 90% liposomal, it is one of the most powerful.
Fisetin
Fisetin is a potent senolytic and SIRT1 activator found naturally in strawberries. It targets
and clears senescent cells, crosses the blood-brain barrier for direct neuroprotection, inhibits
the PI3K/mTOR ageing signalling pathway, and has demonstrated lifespan extension in
animal models. David Sinclair takes 500mg daily. Immortal delivers it liposomal. Paired
with quercetin, its senolytic effect is amplified.
EGCG — Epigallocatechin Gallate
The most bioactive catechin in green tea and one of the most studied polyphenols in
longevity research. EGCG activates AMPK — the cellular energy sensor that triggers
mitochondrial repair, fat oxidation, and autophagy. It inhibits mTOR, the pathway
associated with accelerated cellular ageing when chronically overactive. It also supports
telomere integrity, reduces inflammatory cytokine production, and crosses the blood-brain
barrier for direct neuroprotection.
L-Theanine
L-Theanine is the amino acid responsible for the calm focus of green tea. In the context of a
longevity stack, it plays a specific role: it reduces cortisol-driven neuroinflammation,

supports GABA and dopamine synthesis, and promotes alpha brain wave activity.
Chronically elevated cortisol accelerates cellular ageing via telomere attrition and
mitochondrial dysfunction. L-Theanine is the stack's stress-axis modulator — often
overlooked, always essential.
Astragalus
Astragalus contains cycloastragenol — one of the only compounds in existence demonstrated
to activate telomerase, the enzyme that extends and repairs telomere length. Telomere
attrition is one of the nine recognised hallmarks of ageing. In a double-blind clinical trial,
astragalus extract increased average telomere length and reduced the percentage of critically
short telomeres. Astragalus is the only compound in Immortal — and one of very few in
existence — that directly addresses this hallmark.
TMG — Trimethylglycine
TMG is the methylation insurance policy for the entire formula. When NMN raises NAD+
levels, it increases the body's demand on methyl group supply. TMG donates methyl groups
to prevent this drain — ensuring elevated NAD+ metabolism doesn't deplete the methylation
reserves critical for DNA repair, gene expression regulation, and homocysteine conversion.
David Sinclair includes TMG specifically because of NMN. Immortal does the same.
Piperine
Black pepper extract standardised for piperine. Its function is precise: it inhibits the liver
enzymes and intestinal transporters responsible for first-pass clearance of polyphenols and
flavonoids. Piperine increases the absorption of resveratrol, quercetin, fisetin, and EGCG by
documented multiples. In a liposomal formula already operating at elevated bioavailability,
piperine compounds the effect of every other compound in the stack.
Spermidine
Spermidine is a polyamine found in every cell whose concentration decreases with age. It is
the most studied caloric restriction mimetic — inducing autophagy (cellular housekeeping)
through the same biochemical pathway as fasting, without fasting. It maintains
mitochondrial function, reduces inflammation, protects stem cells from ageing, and has been
linked to improved memory performance and reduced telomere attrition in human studies.
Oral bioavailability of standard spermidine is poor. Liposomal encapsulation addresses this
directly.

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GHK-CU — THE COMPOUND THAT SEPARATES
IMMORTAL

Copper Tripeptide (Glycyl-L-Histidyl-L-Lysine) · 2.5mg Liposomal

You will not find GHK-Cu liposomal in a capsule-format longevity supplement anywhere else
on the market. This is the compound the Mad Scientist built the formula around.

At age 20 your plasma GHK-Cu is 200 ng/ml. By age 60 it has
dropped to 80 ng/ml. That 60% decline is not coincidence. It

is mechanism.

GHK-Cu is a naturally occurring copper-binding tripeptide first isolated from human plasma
in 1973. Almost five decades of research have established what it does at the genetic level —
and the findings are extraordinary.

GENE REPROGRAMMING
GHK-Cu modulates the expression of over 4,000 human genes — silencing inflammatory
and ageing-related genes while activating DNA repair, antioxidant defence, collagen
synthesis, and tissue regeneration pathways. Age-related changes in gene expression that
were once considered permanent have been demonstrated to be reversible.
MITOCHONDRIAL RESTORATION
GHK-Cu restored youthful mitochondrial activity and normalised oxidative stress markers in
fibroblast models. It activates cytochrome c oxidase — the critical copper-dependent enzyme
in the mitochondrial electron transport chain — directly supporting ATP production. Copper
homeostasis in the mitochondria is non-negotiable for energy output. GHK-Cu maintains it.
ANTIOXIDANT DOMINANCE
GHK-Cu quenches hydroxyl and peroxyl radicals more powerfully than glutathione — the
body's own master antioxidant. At concentrations as low as 10μM it reduces reactive oxygen
species in cells by nearly 50%. It activates superoxide dismutase (SOD), lysyl oxidase, and
ceruloplasmin — the three primary copper-dependent enzymes governing antioxidant
defence, connective tissue integrity, and copper transport in serum.
STRUCTURAL REBUILD
GHK-Cu stimulates collagen, elastin, and glycosaminoglycan synthesis simultaneously — not
just in skin, but in lung connective tissue, bone, liver, and gastrointestinal lining. This is
whole-body structural regeneration driven by a single compound at picomolar
concentrations.
NEUROPROTECTION
GHK-Cu regulates copper homeostasis in the brain — disrupted copper balance is a leading
causative factor in Alzheimer's and Parkinson's disease. It stimulates BDNF (brain-derived
neurotrophic factor), VEGF, and nerve growth factor, supporting neuronal repair and
outgrowth. Preliminary research has shown partial reversal of age-associated cognitive
impairment via anti-inflammatory and epigenetic pathways.
ANTI-INFLAMMATORY AT SOURCE
GHK-Cu reduces TNF-α and IL-6 — the two primary cytokines driving chronic systemic
inflammation and virtually every age-related disease downstream of it. It does this not by
suppressing immune function, but by regulating gene expression at the source.

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BIOAVAILABILITY — WHY LIPOSOMAL CHANGES
EVERYTHING

COMPOUND STANDARD LIPOSOMAL
NMN 25% 84%
NR 30% 85%
NAD+ 5% 65%
L-Carnitine 1% 90%
Resveratrol 1% 90%

Every ingredient in Immortal exists in standard supplement form elsewhere. None of them
work properly in standard form. Liposomal delivery is not a marketing claim. It is the only
reason this formula does what it does.

— — —

"Formulate To Destroy."

60 Capsules · Vegan · GMP Certified · Gluten Free
www.spawnnutra.com · www.madscientist5150.com